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Thus, SP may function by interfering with the protein degradation process of KEAP1

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Although the precise mechanisms of HSD17B13 variants in MASH remain unclear, studies have identified that protein kinase A-mediated phosphorylation of HSD17B13 interacts with adipose triglyceride lipase to promote lipolysis and suppress MASH 66

The study also revealed a potential knowledge gap, as participants often overestimated their fruit and vegetable intake in self-reports compared to their detailed food records, suggesting a need for better dietary education on portion sizes

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